Weather Data Source: New York City 30 days weather

New York City Reports Severe Flu Cases Linked to New H3N2 Mutation

People in New York City wearing masks during flu season

New York City, November 26, 2025

New York City is facing a significant rise in severe influenza cases due to a new mutation of the H3N2 strain, called subclade K. This variant is linked to more severe illness and has become the dominant flu strain in several countries, raising concerns among health officials about its ability to evade immunity from vaccinations. Symptoms are consistent with typical influenza, and vaccination remains a crucial preventive measure. Residents are advised to follow health guidelines to mitigate the spread.

New York City Reports Severe Flu Cases Linked to New H3N2 Mutation

New York City is experiencing a surge in severe influenza cases attributed to a newly identified mutation of the H3N2 strain, known as subclade K. This variant has been linked to more severe illness and has become the dominant strain in several countries, including Japan, the United Kingdom, and Canada.

Impact on Public Health

The emergence of subclade K has raised concerns among health officials due to its potential to evade immunity from previous infections and vaccinations. Early data suggest that the current flu vaccine may offer reduced protection against this variant, particularly among older adults.

Symptoms and Transmission

Symptoms of the new flu strain are consistent with typical influenza, including fever, cough, sore throat, runny or stuffy nose, muscle or body aches, headaches, fatigue, and, in some cases, vomiting and diarrhea. The virus spreads through respiratory droplets when an infected person coughs or sneezes.

Preventive Measures

Health experts emphasize the importance of vaccination, even though the current vaccine may be less effective against subclade K. Additional preventive measures include wearing masks in crowded indoor spaces, frequent handwashing, and avoiding close contact with sick individuals.

Background on H3N2 Influenza

The H3N2 strain has been a significant cause of seasonal flu outbreaks since its emergence in 1968. Over the years, it has undergone various mutations, leading to the development of new subclades like K. These mutations can affect the virus’s transmissibility and severity, making ongoing surveillance and adaptation of vaccines crucial.

Current Situation in New York City

As of November 26, 2025, New York City health authorities are closely monitoring the situation. While the exact number of severe cases linked to subclade K is still being assessed, residents are advised to stay informed and adhere to public health guidelines to mitigate the spread of this flu variant.

Frequently Asked Questions (FAQ)

What is subclade K?

Subclade K is a newly identified mutation of the H3N2 influenza A strain, characterized by several genetic changes that may lead to more severe illness and reduced vaccine effectiveness.

How does subclade K differ from other flu strains?

Subclade K carries mutations that allow it to partially evade immunity from previous infections and vaccinations, potentially leading to more severe illness compared to other flu strains.

Are current flu vaccines effective against subclade K?

While the current flu vaccine provides some protection, it may be less effective against subclade K due to the virus’s mutations. Vaccination remains important to reduce the risk of severe illness.

What are the symptoms of subclade K infection?

Symptoms include fever, cough, sore throat, runny or stuffy nose, muscle or body aches, headaches, fatigue, and, in some cases, vomiting and diarrhea.

How is subclade K transmitted?

The virus spreads through respiratory droplets when an infected person coughs or sneezes, and by touching surfaces contaminated with the virus.

What preventive measures should be taken?

Health experts recommend vaccination, wearing masks in crowded indoor spaces, frequent handwashing, and avoiding close contact with sick individuals to prevent the spread of subclade K.

Key Features of Subclade K Flu Variant

Feature Description
Mutation Subclade K is a mutated version of the H3N2 influenza A strain, carrying several genetic changes.
Severity Associated with more severe illness compared to other flu strains.
Vaccine Effectiveness Current flu vaccines may offer reduced protection against subclade K due to its mutations.
Symptoms Similar to typical flu symptoms: fever, cough, sore throat, runny or stuffy nose, muscle or body aches, headaches, fatigue, and, in some cases, vomiting and diarrhea.
Transmission Spreads through respiratory droplets when an infected person coughs or sneezes, and by touching contaminated surfaces.
Preventive Measures Vaccination, wearing masks in crowded indoor spaces, frequent handwashing, and avoiding close contact with sick individuals.

Now Happening on X

  • @honeyybomb (November 25, 2025, 1:03 PM): Residents in Queens reported a mob attack on a couple trying to maintain neighborhood safety, including beating them and setting a car on fire with fireworks, while 911 was overwhelmed and redirected calls to a quality of life team. View on X
  • @NY_Scoop (October 31, 2025, 1:57 AM): Heavy rain caused severe flooding in New York City, overwhelming infrastructure with subway stations and highways turning into rivers, stranding passengers and disrupting transit. View on X
  • @s2_underground (November 5, 2025, 2:24 AM): Election Day in NYC faced multiple bomb threats and voting disruptions, alongside White House confirmation of SNAP program cessation amid a government shutdown and a major plane crash at Louisville airport. View on X
  • @honeyybomb (November 25, 2025, 1:01 PM): A mob in Queens overran streets, assaulted a couple, and burned a car using fireworks amid laughter and filming, as short-staffed 911 dispatch instructed residents to call 311 instead of sending police. View on X
  • @SharylAttkisson (November 19, 2025, 3:03 PM): NYC crime, including subway slashings and rising antisemitic attacks, is a key debate amid concerns over law and order following the election of incoming socialist mayor Zohran Mamdani. View on X
  • @foxydude_honest (November 23, 2025, 4:42 PM): A child’s terrifying 911 call during a domestic incident highlights chaos in NYC, raising questions about the new mayor’s plan to send social workers instead of police to such cases. View on X
  • @SPECNews1CNY (November 24, 2025, 10:13 PM): Evening briefing on New York includes an ex-assistant DA suing the Onondaga County DA’s office, calls for Governor Hochul to address affordability, and expectations of record Thanksgiving travel. View on X
  • @LaurenW66346287 (November 20, 2025, 10:12 PM): Discussion on NYC’s new mayor Zohran Mamdani’s potential meeting with Trump, retention of the female police chief, and impacts of cashless bail under Cuomo leading to underreporting of crimes. View on X
  • @VGupta30 (November 23, 2025, 7:42 PM): Cozen O’Connor’s New York Note covers a council member entering the NY-12 race, city council passing bills on safety and licensing, and advances in Long Island City rezoning. View on X
  • @GenX_noBS (November 23, 2025, 10:00 PM): Reports of cats being set on fire and a security officer assaulted in NYC, with 911 directing car parties to the quality of life team instead of police in the 109 and 111 precincts, questioning public safety response. View on X

Deeper Dive: News & Info About This Topic

HERE Resources

STAFF HERE NEW YORK WRITER
Author: STAFF HERE NEW YORK WRITER

The NEW YORK STAFF WRITER represents the experienced team at HERENewYork.com, your go-to source for actionable local news and information in New York, the five boroughs, and beyond. Specializing in "news you can use," we cover essential topics like product reviews for personal and business needs, local business directories, politics, real estate trends, neighborhood insights, and state news affecting the area—with deep expertise drawn from years of dedicated reporting and strong community input, including local press releases and business updates. We deliver top reporting on high-value events such as New York Fashion Week, Macy's Thanksgiving Day Parade, and Tribeca Film Festival. Our coverage extends to key organizations like the Greater New York Chamber of Commerce and United Way of New York, plus leading businesses in finance and media that power the local economy such as JPMorgan Chase, Goldman Sachs, and Bloomberg. As part of the broader HERE network, including HEREBuffalo.com, we provide comprehensive, credible insights into New York's dynamic landscape.

Advertising Opportunity:

Stay Connected

More Updates

Would You Like To Add Your Business?

Sign Up Now and get your local business listed!